Shiro Sano (佐野 史郎, Sano Shirō, born 4 March 1955) is a Japanese actor.

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Shiro Sano is a veteran Japanese actor and director born in Yamanashi, recognized for his extensive work in cinema and television since the 1980s.
He is widely known for his performance in Takeshi Kitano's 'Violent Cop', his various roles in the Godzilla franchise including 'Godzilla, Mothra and King Ghidorah', and the fantasy classic 'Tokyo: The Last Megalopolis'.
He is celebrated for his versatility, frequently portraying eccentric intellectuals, villains, and authoritative figures across genres ranging from horror and sci-fi to comedy and drama.